DMD # 48736 1 Generation and Characterization of a Novel Cyp 2 a ( 4 / 5 ) bgs - null Mouse Model
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Dmd048736 132..140
Knockout mouse models targeting various cytochrome P450 (P450 or CYP) genes are valuable for determining P450’s biologic functions, including roles in drug metabolism and chemical toxicity. In this study, a novel Cyp2a(4/5)bgs-null mouse model was generated, in which a 1.2-megabase pair genomic fragment containing nine Cyp genes in mouse chromosome 7 (including, sequentially, Cyp2a5, 2g1, 2b19,...
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تاریخ انتشار 2012